Abstract Ferroptosis, a novel form of cell death triggered by iron-dependent phospholipid peroxidation, presents significant therapeutic potential across diverse cancer types.Central to cellular metabolism, the metabolic pathways associated with ferroptosis are discernible in new belial model both cancerous and immune cells.This review begins by de
Renal cell carcinoma (RCC) is the most common solid tumour of the kidney and accounts for 3% of all cancers.While immune checkpoint inhibitor (ICI)-based combination therapies have emerged as the first-line treatment for metastatic renal cell carcinoma (mRCC), the role of surgery has become more controversial.This review summarizes the evidence, cu
Abstract Background Mediastinum abscess caused by sharp esophageal foreign body perforation usually needs surgical treatment, and the surgical procedures vary according to size of perforation and scope of abscess, etc.For special case with small esophageal mucosal crevasse and focal abscess confined to mediastinum, minimally invasive surgery with g
This paper aims to develop a novel hierarchical recursive nonsingular terminal sliding mode controller (HRNTSMC), which is designed to stabilize the inverted pendulum (IP).In contrast to existing hierarchical sliding mode controllers (HSMC), the HRNTSMC significantly reduces the chattering problem in control input and improves the convergence speed
Metabolic reprogramming is a hallmark of cancer.Somatic mutations in genes involved in oncogenic signaling pathways, including KRAS and TP53, rewire the metabolic machinery in cancer cells.We here set out to determine, at the single cell level, metabolic signatures in human colon cancer cells engineered to express combinations of activating KRAS ge